Relieve, reduce and treat with Daflon 1000
Daflon 1000 is an oral treatment for heavy, painful legs, varicose veins and other symptoms of poor leg vein health.
Answer 5 short questions to assess your symptoms and risk factors
Heavy, Painful Legs?
Legs that feel heavy, painful and swollen can be a result of a build up of fluid in the legs due to the blood not circulating as well as it should. This increased fluid leads to the symptoms of Chronic Venous Insufficiency, a condition affecting leg vein health that worsens over time. 2
Healthy Veins
Healthy veins have small valves which prevent blood flowing backwards.
Unhealthy Veins
When the internal walls of the veins are damaged, and these valves don’t work as well, blood can flow back into the veins, resulting in pooling in the lower leg and leading to dilated veins and uncomfortable symptoms that can worsen over time.
Symptoms of Poor Blood Flow
A range of signs and symptoms can point to poor blood flow in the legs. If you’ve been experiencing any of the following symptoms in your legs or ankles you should seek treatment as they can worsen over time.
Heavy, Painful or Swollen Legs
Tired Legs
Cramping or Leg pain
Spider or Varicose veins
Looks familiar?
If you regularly suffer from at least one of these symptoms, take our quick self-assessment quiz and use your result to help guide your next steps.
Treat Your Symptoms Early
Heavy, painful legs and swelling can be early signs of chronic venous insufficiency. Left untreated, these symptoms can increase in severity, leading to spider veins, varicose veins, and leg ulcers. The different stages of disease are described as grades C0-6 depending on the severity of the symptoms as shown here:
Stage 0
Heavy, Painful Legs
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Stage 0
Heavy, Painful Legs
The first stage, with no visible signs of venous disease. However, damage may already be starting to accumulate inside the vein. This leads to venous reflux and is why you should start treating, even if your only symptoms are heavy and painful legs.
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Stage 1
Spider/Reticular Veins
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Stage 1
Spider/Reticular Veins
Ignoring initial symptoms can cause the condition to worsen, leading to broken blood vessels or “spider veins” and visible veins. They aren’t usually painful, but are an important indicator of leg vein problems. It’s important not to ignore this early sign as the condition can rapidly progress.
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Stage 2
Visible varicose veins
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Stage 2
Visible varicose veins
Left untreated, stage 1 turns to stage 2 with the veins becoming unusually dilated, stretched out and sinuous. These obvious, bulging veins on the legs and ankles are a clear sign of chronic venous insufficiency.
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Stage 3
Swelling of the ankle and leg
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Stage 3
Swelling of the ankle and leg
Edema (swelling) may appear in stage 3 caused by increased pressure and leakage as a result of further deterioration of the venous walls and valves.
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Stage 4
Skin changes
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Stage 4
Skin changes
Continued poor circulation can lead to stage 4, characterised by darkening of the skin around your ankles (hyperpigmentation), redness, dryness, itchiness (venous eczema), hardening of soft tissues and the development of whitish patches.
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Stage 5
Healed ulcers
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Stage 5
Healed ulcers
Stage 5 is defined by the presence of open but healed areas of skin called ulcers. These can be painful and affect your quality of life, making it difficult to move around.
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Stage 6
Active ulcers
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Stage 6
Active ulcers
If you reach stage, you will have open wounds called ulcers on your legs. Internally at this stage there is more deterioration in circulation and increased leakage in the capillaries.
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If you are experiencing any of these signs and symptoms you should speak with a health care professional about treatment options.
By recognising the symptoms and taking action, you can significantly reduce the likelihood of your condition progressing and lessen the impact on your day-to-day life.
RISK FACTORS YOU CAN CONTROL
Standing for long periods
Being overweight
RISK FACTORS YOU CAN'T CONTROL
Age
Gender
Genetics
Factors Affecting Blood Circulation
There are several key risk factors for Chronic Venous Insufficiency, some of which may be beyond your control, but others you can take steps to modify. 1
Women are typically more at risk, and a family history, as well as simply growing older can increase your chances of developing symptoms.
Lifestyle factors you can take steps to negate, such as being overweight and inactive, can also increase your risk of developing problems with your veins. Those who stand or sit as part of their occupations, such as nurses, teachers and those in the service industry, are particularly at risk.
Don’t Let Your Legs Hold You Back.
One tablet, once daily to relieve painful leg symptoms.
Advice for Healthy Legs
By incorporating simple habits into your daily routine and maintaining a healthy lifestyle, you can help protect your legs from the discomfort caused by increased fluid in your legs and the damage this can cause to veins over time:
Stay active
Regular exercise helps improve circulation and tone the muscles in your legs.
Wear compression stockings
Compression stockings help to improve blood circulation in the legs.
Maintain a healthy weight
Keep a close eye on your weight as obesity can contribute to blocked or weakened valves in leg.
Avoid high heels
Choose a medium heel over flat or high-heeled shoes to encourage more lower leg activity.
Wear loose clothing
Avoid tight clothing which can restrict blood flow in the legs and exacerbate risk of chronic venous insufficiency.
Stay cool
Veins dilate in the heat which can cause blood to pool and contribute to your legs feeling heavy and tired.
Move regularly
Avoid sitting or standing for too long to prevent blood pooling in your leg veins and help blood flow to the heart.
Elevate your legs
Raise your legs and avoid crossing them to help blood flow towards the heart when relaxing.
In addition to lifestyle modifications, topical creams and gels can be used for symptom relief, and medical procedures can treat the advanced condition.
Daflon 1000 is available in all pharmacies
Frequently Asked Questions
Treatment of chronic venous insufficiency is essential to maintaining healthy legs. If you think you are suffering from this progressive condition, speak with a health care professional about the best treatment(s) for you.
What is Daflon used for?
Daflon is an oral treatment that helps to relieve the signs and symptoms of mild-to-moderate chronic venous insufficiency, such as varicose and spider veins, leg pain, leg cramps and the sensation of heavy legs. It also helps to reduce lower leg edema associated with the condition.
Do I need a prescription for Daflon?
No. Daflon is an over-the-counter treatment. If you can’t find it, your pharmacist should be able to order it for you.
How does Daflon 1000 work?
Daflon works by improving vein tone for better circulation and reduced pain, lower leg swelling and sensation of heaviness in the legs. Daflon works by improving the tone of the veins to improve venous circulation. It helps to reduce leg symptoms related to venous disease such as heaviness, pain, swelling.
What is Daflon 1000 ?
Daflon’s active ingredient is a micronized purified flavonoid fraction (MPFF). It is composed of citrus bioflavonoids, containing 90% diosmin and 10% other flavonoids expressed as hesperidin.
What does micronized mean?
Micronized means that a substance has been broken into very small particles for more effective absorption
How do I take Daflon correctly for Chronic Venous Insufficiency?
Simply take 1 tablet of Daflon 1000 once a day, or as directed by your healthcare practitioner.
How long should I take Daflon 1000 for?
Daflon 1000 is a continuous treatment for an ongoing progressive condition. It is recommended that you continue to take Daflon unless otherwise directed by your doctor or pharmacist.
I take a lot of medication, can Daflon 1000 be taken with other medications?
You should speak with your doctor and discuss whether Daflon 1000 is safe to combine with your other medications.
How tolerated is Daflon 1000 ?
Daflon is well tolerated, and side effects observed in trials were mild. Possible side effects include hypersensitivity/allergy, gastrointestinal discomfort, dizziness, headaches, malaise, and skin reactions.
Safety Information:
Daflon 1000 mg Safety Information
Daflon 1000:
Micronised, purified flavonoic fraction 1000 mg quantity corresponding to: Diosmin 90 % 900 mg Flavonoids expressed as hesperidin 10 % 100 mg Average moisture content 40 mg per film-coated tablet.
INDICATIONS
It is recommended for treating venous circulation disorders (swollen legs, pain, restless legs) and symptoms due to acute hemorrhoidal attack. If the haemorrhoidal episodes persist for more than 15 days, it is essential that you consult your doctor.
It is indicated in the treatment of functional menorrhagia and premenstrual syndrome.
DOSAGE AND ADMINISTRATION
Always take DAFLON 1000 mg exactly as your doctor has described. If you are not sure, you should check with your doctor or pharmacist. The usual dose is 1 tablet daily at mealtimes. If you take this medicine for a haemorrhoidal episode, the usual dose is 3 tablets per day for 4 days and then 2 tablets per day for the next 3 days at mealtimes.
CONTRAINDICATIONS
If you are allergic (hypersensitive) to micronised purified flavonoid fraction, especially diosmin (or hesperidin), or any of the other ingredients in this medicine.
WARNINGS
Warnings and precautions
Ask your doctor or pharmacist for advice before taking Daflon 1000 mg, film-coated tablet.
Children
This medication is not applicable for use in children.
Taking or using other medicines with Daflon 1000 mg, film-coated tablet
Please tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.
Taking Daflon 1000 mg, film-coated tablet with food and drinks
Not applicable.
Pregnancy and breastfeeding
Pregnancy: If you become pregnant during your treatment, or if you are pregnant and plan to take this medicine, ask your doctor or pharmacist for advice.
Breastfeeding: Breast-feeding is inadvisable for the duration of the treatment, due to the absence of data on the passage of the medicine into breast milk. Ask your doctor or pharmacist for advice before taking any medicine.
Sports
Not applicable.
Driving and using machines
Not applicable.
Excipients
- Sodium starch glycolate
- Microcrystalline cellulose
- Gelatine
- Magnesium stearate
- Talc
Film coating: Titanium dioxide (E 171), glycerol, sodium laurylsulphate, macrogol 6000, hypromellose, yellow iron oxide (E 172), red iron oxide (E 172), magnesium stearate.
Possible side effects
- Common: diarrhoea, dyspepsia, nausea, vomiting.
- Uncommon: colitis.
- Rare: dizziness, headache, malaise, rash, pruritus, urticaria.
- Not known frequency: abdominal pain, isolated face, lip, eyelid oedema. Exceptionally Quincke's oedema
If you take more Daflon 1000 mg, film-coated tablet, than you should: Consult immediately your doctor or pharmacist. An overdosage of this medicine can make side effects worse.
PROPERTIES
Pharmacotherapeutic class: VASCULOPROTECTORS/ MEDICINES ACTING ON CAPILLARIES/ BIOFLAVONOIDS
This medicine is a venotonic (it increases venous tone) and a vasculoprotector (it increases resistance in small blood vessels).
To report suspected Adverse Drug Reaction kindly fill this form
References:
- Adapted from Nicolaides A, Kakkos S, Baekgaard N, et al. Management of chronic venous disorders of the lower limbs.
- Guidelines according to scientific evidence. Part I. Int Angiol. 2018;37(3):181-254.1 Bergan JJ et al. N Engl J Med. 2006;355:488-4981.
