Daflon 1000. For the Relief and Prevention of Hemorrhoidal disease.
How does Daflon 1000 work?
Daflon 1000 is a convenient oral venoactive treatment that gets to the root of hemorrhoid problems by working to treat the veins that become dilated and inflamed during a hemorrhoidal episode.1
Daflon 1000 quickly works to treat hemorrhoidal disease by reducing the associated signs and symptoms of the disease and can also strengthen the overall tone of your veins, helping to improve blood flow and reducing venous congestion for long term management of hemorrhoids. 1
Daflon 1000 is available in all pharmacies
Formulated for Fast Absorption and Relief
Daflon 1000 is a clinically proven, effective and discrete oral treatment derived from natural ingredients and specially formulated for maximum absorption. 1
This improved absorption means Daflon 1000 can rapidly get to the root of the problem to conveniently and discretely reduce the duration, intensity and recurrence of hemorrhoid episodes, with different dosing options for fast-acting treatment of acute episodes, or ongoing maintenance for recurring hemorrhoid disease. 2
Rapid Relief
Daflon 1000 is clinically proven to quickly and effectively treat hemorrhoidal episodes for rapid relief. 1,2 In just two days, 42% of users demonstrated a reduction in their symptoms and in only three days, 80% reported that their bleeding had stopped. After a single week, most people reported that their symptoms, including bleeding, pain and discharge had resolved.
Rapid relief for Acute Hemorrhoids
At 2 days
42% of patients experienced mild reduction of symptoms
At 3 days
80% of patients' bleeding stopped 2
At 7 days
94% of patients' bleeding stopped 2 84% of patients' pain stopped 4 81% of patients' discharge stopped 4
Why you should treat continuously
Hemorrhoidal disease is a progressive inflammatory condition which can be treated but can also recur. In fact, one in four patients may experience hemorrhoids again within 7 months of a resolved episode. 7
Daflon 1000 is a venoactive drug treatment recommended for the treatment of all grades of hemorrhoidal disease.1 By treating early and regularly with Daflon you can help prevent the recurrence of acute hemorrhoidal episodes and reduce the severity of symptoms. 5
Convenient Oral Dosing
The personal nature of hemorrhoid symptoms might put you off seeking treatment. Daflon 1000 offers the convenience of a discreet over-the-counter oral treatment that quickly and effectively manages hemorrhoid symptoms and treats their root cause, letting you get back to you. 2
One week treatmentfor Acute Hemorrhoids
First 4 days:3 tabletsa day
Next 3 days:2 tabletsa day
Naturally sourced, scientifically prepared.
The active ingredient in Daflon is a micronized purified flavonoid fraction (MPFF)6 containing 90% diosmin and 10% other flavonoids expressed as hesperidin.
Daflon’s flavonoids are extracted from immature oranges that are rich in these naturally occurring plant chemicals. The compounds undergo a process of purification and refinement where the particles are made to collide with each other at high speeds (micronization), reducing them to tiny particles, less than 2 μm in size (micronized). These smaller particles are absorbed twice as easily by the body and are a key ingredient of Daflon’s success as a treatment for improving vein health and tone in Chronic Venous Insufficiency and Hemorrhoids. 6
Safety Information:
Daflon 1000 mg Safety Information
Daflon 1000:
Micronised, purified flavonoic fraction 1000 mg quantity corresponding to: Diosmin 90 % 900 mg Flavonoids expressed as hesperidin 10 % 100 mg Average moisture content 40 mg per film-coated tablet.
INDICATIONS
It is recommended for treating venous circulation disorders (swollen legs, pain, restless legs) and symptoms due to acute hemorrhoidal attack. If the haemorrhoidal episodes persist for more than 15 days, it is essential that you consult your doctor.
It is indicated in the treatment of functional menorrhagia and premenstrual syndrome.
DOSAGE AND ADMINISTRATION
Always take DAFLON 1000 mg exactly as your doctor has described. If you are not sure, you should check with your doctor or pharmacist. The usual dose is 1 tablet daily at mealtimes. If you take this medicine for a haemorrhoidal episode, the usual dose is 3 tablets per day for 4 days and then 2 tablets per day for the next 3 days at mealtimes.
CONTRAINDICATIONS
If you are allergic (hypersensitive) to micronised purified flavonoid fraction, especially diosmin (or hesperidin), or any of the other ingredients in this medicine.
WARNINGS
Warnings and precautions
Ask your doctor or pharmacist for advice before taking Daflon 1000 mg, film-coated tablet.
Children
This medication is not applicable for use in children.
Taking or using other medicines with Daflon 1000 mg, film-coated tablet
Please tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.
Taking Daflon 1000 mg, film-coated tablet with food and drinks
Not applicable.
Pregnancy and breastfeeding
Pregnancy: If you become pregnant during your treatment, or if you are pregnant and plan to take this medicine, ask your doctor or pharmacist for advice.
Breastfeeding: Breast-feeding is inadvisable for the duration of the treatment, due to the absence of data on the passage of the medicine into breast milk. Ask your doctor or pharmacist for advice before taking any medicine.
Sports
Not applicable.
Driving and using machines
Not applicable.
Excipients
- Sodium starch glycolate
- Microcrystalline cellulose
- Gelatine
- Magnesium stearate
- Talc
Film coating: Titanium dioxide (E 171), glycerol, sodium laurylsulphate, macrogol 6000, hypromellose, yellow iron oxide (E 172), red iron oxide (E 172), magnesium stearate.
Possible side effects
- Common: diarrhoea, dyspepsia, nausea, vomiting.
- Uncommon: colitis.
- Rare: dizziness, headache, malaise, rash, pruritus, urticaria.
- Not known frequency: abdominal pain, isolated face, lip, eyelid oedema. Exceptionally Quincke's oedema
If you take more Daflon 1000 mg, film-coated tablet, than you should: Consult immediately your doctor or pharmacist. An overdosage of this medicine can make side effects worse.
PROPERTIES
Pharmacotherapeutic class: VASCULOPROTECTORS/ MEDICINES ACTING ON CAPILLARIES/ BIOFLAVONOIDS
This medicine is a venotonic (it increases venous tone) and a vasculoprotector (it increases resistance in small blood vessels).
To report suspected Adverse Drug Reaction kindly fill this form
References
- Shelygin Y, Krivokapic Z, Frolov SA, et al. Clinical acceptability study of micronized purified flavonoid fraction 1000 mg tablets versus 500 mg tablets in patients suffering acute hemorrhoidal disease. Curr Med Res Opin. 2016;32(11):1821-1826.
- Misra MC, Parshad R. Randomized clinical trial of micronized flavonoids in the early control of bleeding due to acute internal hemorrhoids. Br J Surg. 2000;87:868-872.
- Garner RC, Garner JV, Gregory S, Whattam M, Calam A, Leong D. Comparison of the absorption of micronized (Daflon 500 mg) and nonmicronized 14C-diosmin tablets after oral administration to healthy volunteers by accelerator mass spectrometry and liquid scintillation counting. J Pharm Sci. 2002;91:32-40.
- Cospite M. Double-blind, placebo-controlled evaluation of clinical activity and safety of Daflon 500 mg in the treatment of acute hemorrhoids. Angiology. 1994;45:566-573.
- Godeberge P. Daflon 500mg is significantly more effective than placebo in the treatment of hemorrhoids. Phlebology. 1992;7(suppl 2):61-63.
- Summary of Product Characteristics Daflon 7. Greenspon. Thrombosed external hemorrhoids: outcome after conservative or surgical treatment J.Dis Colon Rectum 2004. 47(9):1493-8.
